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Synthetic testosterone derivatives known as anabolic-androgenic steroids (AAS) are intended to separate the androgenic (masculinizing) and anabolic (tissue-building) effects. They are divided structurally into two main families: those generated from testosterone (such as testosterone enanthate) and those produced from dihydrotestosterone (DHT), such as Winstrol and Anavar. Due to their inability to aromatize to estrogen, the latter class—which includes stanozolol—reduces the negative effects of estrogen, such as gynecomastia and water retention.

Action Mechanism;
In skeletal muscle, bone, and other tissues, AAS binds to intracellular androgen receptors to produce its effects. This complex moves into the nucleus and starts the transcription of genes that control the synthesis of proteins, the retention of nitrogen, and the creation of red blood cells. Furthermore, a number of AAS, such as Winstrol, increase the availability of free testosterone by lowering Sex Hormone-Binding Globulin (SHBG).